Topical Vancomycin for Craniotomies

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This study has been designed as a single-blinded, multi-center, randomized clinical trial at New York Presbyterian Hospital Columbia and New York Presbyterian Hospital Cornell. The study population includes all adult craniotomies performed at each institution over a 4 year and 9 month time period. The treatment variable is the application of topical vancomycin to the surgical site. If a craniotomy is performed, a paste made from vancomycin powder and sterile solution will be applied to the edges and outer surface of the craniotomy. In all cases, the powder will be applied directly to the wound prior to the closure of skin or galea.

Contact Dr. Knopman: 212-746-5149