Contralateral dissociation between neural activity and cerebral blood volume during recurrent acute focal neocortical seizures

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Contralateral dissociation between neural activity and cerebral blood volume during recurrent acute focal neocortical seizures

Whether epileptic events disrupt normal neurovascular coupling mechanisms locally or remotely is unclear. We sought to investigate neurovascular coupling in an acute model of focal neocortical epilepsy, both within the seizure onset zone and in contralateral homotopic cortex.

Publication Name: 
Epilepsia
Authors: 
Sam Harris, Luke Boorman, Michael Bruyns-Haylett, Aneurin Kennerley, Hongtao Ma, Mingrui Zhao, Paul G. Overton, Theodore H. Schwartz, and Jason Berwick