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Dr. Souweidane’s Phase 1 Trial Findings Published in Lancet Oncology

Mark M Souweidane, MD, Weill Cornell Medicine

Today, the peer-reviewed journal Lancet Oncology published the highly anticipated results of Dr. Mark Souweidane’s first-ever dose escalation study using convection-enhanced delivery (CED) in patients with diffuse intrinsic pontine glioma (DIPG). The milestone Phase I clinical trial, which investigated the safety of using CED to bypass the blood-brain barrier and administer a drug directly to a brain stem tumor site, resulted in no serious adverse effects and no dose-limiting toxicity; researchers conclude that the technique is safe to use in children.

Best Neurosurgeons in New York, 2018

New York Magazine Best Doctors 2018 - Weill Cornell Medicine Neurosurgeons

The annual list of “Best Doctors in New York,” published this week by New York magazine, includes eight of our faculty members

11 Faculty Members Selected to 2018 List of New York SuperDoctors

11 Weill Cornell Medicine Neurosurgery Faculty Members Selected to 2018 List of New York SuperDoctors

The annual list, published each May in the New York Times Magazine, is assembled based on peer nomination, credentials, and achievement.

Weill Cornell Medicine Neurological Surgery Residents Selected at Match Day 2018

Weill Cornell Medicine Neurological Surgery Residents Selected at Match Day 2018

We welcome Maricruz Rivera and Gary Kocharian, who will be joining our program in June.

Dr. Rajappa Presents at Pediatric Precision Oncology Conference

Dr. Prajwal Rajappa, Precision Medicine Fellow in Dr. Jeffrey Greenfield’s pediatric brain tumor research lab at Weill Cornell Medicine

The Pediatric Precision Medicine Fellow presented “Precision Sequencing Algorithm for Pediatric Neuro-Oncology”

Dr. Greenfield Named Vice Chair of Academic Affairs

Dr. Jeffrey Greenfield

In his new role, Dr. Greenfield will oversee and manage all of the department's diverse educational programs

Dr. Cisse Named As Winner of NINDS-CNS Getch Scholar Award

Dr. Babacar Cisse

The award was established in 2015 to support the research efforts of promising neurosurgeon-scientists.

Dr. Greenfield Named to List of Top Doctors 2017

Dr Jeffrey Greenfield, Weill Cornell Medicine

Dr. Greenfield joins 9 of his colleagues from the Weill Cornell Brain and Spine Center who had previously earned this distinction.

Dr. Souweidane Named to NCI’s Brain Malignancies Steering Committee

Dr. Mark Souweidane, Weill Cornell Brain and Spine Center

The committee is charged with reviewing and prioritizing Phase 2 and Phase 3 clinical trial concepts, in order to promote the best clinical and translational research for patients with brain cancer.

Lyonhearted Foundation Funds New DIPG Project

Jason Lyon, Lyonhearted Foundation

Thanks to a gift from the Lyonhearted Foundation of southern California, Dr. Mark Souweidane and Dr. Uday Maachani will initiate a new research project in the Children’s Brain Tumor Project laboratory. The team expects the new investigation to validate the use of cell-free tumor  DNA (cf-DNA) as a biomarker of the disease burden in children with diffuse intrinsic pontine glioma (DIPG).

DIPG Paper Selected as Cover Story in JNS Pediatrics

Dr Peter Morgenstern, Dr. Mark Souweidane, and MD/PhD student Iryna Ivasyk

A case study that suggests CED remains a viable treatment option for lesions with cysts

Influence of an intratumoral cyst on drug distribution by convection-enhanced delivery: A case report

Journal of Neurosurgery Pediatrics: Sept 2017

Convection-enhanced delivery (CED) uses positive pressure to induce convective flow of molecules and maximize drug distribution.

Dr. Souweidane to Speak at SNO Pediatrics Conference

Mark Souweidane, MD

There are more findings to report from his landmark clinical trial for DIPG

Best Neurosurgeons in New York, 2017

New York Magazine, Top Doctors 2017

This year's list includes 8 of our faculty members

Dr. Souweidane to Present DIPG Clinical Trial Results at ASCO

Dr. Mark Souweidane

The four-plus-year-long trial shows that CED is safe to use in children with DIPG

Nadia Dahmane, PhD, Joins Children’s Brain Tumor Project

Children's Brain Tumor Project

Dr. Dahmane's research examines brain development, including the processes of cell differentiation and proliferation – which, when unchecked, can lead to pediatric tumor development.

CBTP Team Publishes New Findings on DIPG Tumor Imaging

Mark M. Souweidane, MD and CBTP researcher Uday Maachani, PhD

Developing a reliable means of measuring the volume of a DIPG tumor is a significant advance that will greatly aid in the assessment of potential new treatments.

Raymond Chang Wins ABTA Award for Summer Sprint Project

Raymond Chang Wins ABTA Award for Summer Sprint

Raymond Chang, a medical student who participated in the Children’s Brain Tumor Project “summer sprint” in 2016, has been named winner of the American Brain Tumor Association’s Lucien Rubinstein Award.

New Paper Shows How Gliomas May Be Stopped in Their Tracks

Dr. Jeffrey Greenfield and Dr. Prajwal Rajappa of Weill Cornell Medicine

Researchers found how it may be possible to stop the progression of a low-grade, survivable glioma into a high-grade, fatal malignancy.


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