Symptoms of Glioblastoma Multiforme

As with many brain tumors, the most common initial symptom of glioblastoma multiforme is headache. Since the symptoms are often caused by the pressure of a tumor against adjacent brain structures, the symptoms may vary depending on where in the brain or spine the tumor is located. Symptoms of GBM include:

  • Weakness or numbness in the limbs
  • Nausea and vomiting (especially on awakening)
  • Cognitive impairment, memory loss, and inability to concentrate
  • Seizures
  • Personality and mood changes
  • Visual changes

 
Most people with headaches and nausea do not have brain tumors, of course, but anyone with neurological symptoms like those listed above should be evaluated by a physician. Suspected or confirmed brain tumors should be referred to a neurosurgeon for evaluation (see Doctors Who Treat Glioblastoma Multiforme).

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Our Care Team

  • Chairman and Neurosurgeon-in-Chief
  • Margaret and Robert J. Hariri, MD ’87, PhD ’87 Professor of Neurological Surgery
  • Vice Provost of Business Affairs and Integration
Phone: 212-746-4684
  • Chief of Neurological Surgery, NewYork-Presbyterian Brooklyn Methodist
  • Alvina and Willis Murphy Associate Professor, Neurological Surgery
  • Director, Brain Metastases Program
  • Co-director, William Rhodes and Louise Tilzer-Rhodes Center for Glioblastoma
Phone: 212-746-1996
  • Assistant Professor of Neurological Surgery
  • Leon Levy Research Fellow
  • Feil Family Brain and Mind Research Institute
Phone: 646-962-3389
  • Assistant Professor, Neurological Surgery
Phone: 718-670-1837
  • Director, Neurosurgical Radiosurgery
  • Associate Professor of Clinical Neurological Surgery
  • Robert G. Schwager, MD ’67 Education Scholar, Cornell University
Phone: 212-746-2438
  • Chief of Neurological Surgery, NewYork-Presbyterian Queens
Phone: (718) 670-1837
  • Vice Chair for Clinical Research
  • David and Ursel Barnes Professor in Minimally Invasive Surgery
  • Professor of Neurosurgery, Neurology, and Otolaryngology
  • Director, Center for Epilepsy and Pituitary Surgery
  • Co-Director, Surgical Neuro-oncology
Phone: 212-746-5620
  • Director of Neuro-oncology
  • Director, Brain Tumor Center, Sandra and Edward Meyer Cancer Center
Phone: 646-962-2185
  • Assistant Attending Neurologist, NewYork-Presbyterian Hospital
  • Assistant Professor of Neuro-Oncologist
Phone: 646-962-2185

Reviewed by: Rohan Ramakrishna, M.D.
Last reviewed/last updated: December 2020

Weill Cornell Medicine Brain & Spine Center 525 East 68 Street, Box 99 New York, NY 10065 Phone: 866-426-7787