- Assistant Professor of Developmental Biology in Neurological Surgery
Dr. Nadia Dahmane, PhD, has spent her career studying the relationship between developmental biology and cancer. Her work examines normal brain development, including the processes of cell differentiation and proliferation – which, when unchecked, can lead to pediatric tumor development.
Dr. Dahmane’s current research focuses a group of proteins called transcription factors that regulate how different genes are expressed during both brain development and brain cancer progression. Her laboratory has identified a critical novel transcription factor protein (called RP58) that is indispensable for brain development; its deletion in a mouse model leads to microcephaly, a birth defect affecting the size of the brain. New work from her group investigates how this protein may also be involved in brain tumor development.
Dr. Dahmane earned a B.S. in Biology and an M.S. in Biochemistry/Cell Biology from the University of Rouen, France, and she was awarded a Ph.D. in Biology of Aging by the University of Paris, France.